Plexium

San Diego, CA

Plexium is a drug development startup that leverages techniques from various physical science and computational disciplines. The company develops ‘molecular glues’ that alter E3-ligase substrate recognition; inducing, inhibiting, or modulating degradation of proteins for therapeutic benefit. It utilizes DNA-encoded libraries to search for molecular-glue degraders in high throughput cell-based assays. Plexium was founded in 2017 and is based in San Diego, California.