Companies by HQ LocationTech Companies and Startups Headquartered in San Diego

333 companies in this collection.

Nestled along the picturesque coastline of California, San Diego has emerged as a vibrant hub for tech companies that are shaping the digital landscape. Beyond its sun-soaked beaches and cultural allure, the city is nurturing a dynamic ecosystem of tech innovation, from computer software systems to cutting-edge information technology. In this article, we'll explore the tech company landscape in San Diego, highlighting the diversity of industries and the city's commitment to driving technological advancement.

A Fusion of Tech Prowess

San Diego's tech scene encompasses a wide range of industries, each contributing to the city's vibrant ecosystem. From computer software development to information technology services, San Diego is a melting pot of expertise. Companies specializing in systems engineering, internet business, online media, and more are crafting the digital future, pushing the boundaries of innovation.

Tech Companies Paving the Way

San Diego boasts a plethora of tech companies that have made their mark on the industry. From designing and developing cutting-edge software solutions to providing essential consulting and management services, these companies play a vital role in driving the city's tech prowess. Whether it's in the realm of marketing, security, or business intelligence, San Diego's tech companies are forging the path forward.

Innovative Ventures in Information Technology

The city's commitment to information technology is apparent in its thriving landscape of tech companies. From enterprise software development to systems engineering, San Diego's information technology sector is a hotbed of innovation. Companies are pushing the envelope with solutions that streamline operations, enhance efficiency, and enable businesses to harness the power of data and digital connectivity.

Web and Media Innovation

San Diego's tech innovation isn't limited to software and systems; it extends to the realms of internet business and online media. Companies are redefining how we interact with the digital world through web design, online marketing, and media production. San Diego's creative spirit is evident in these ventures, as they strive to captivate audiences and make a lasting impact in the digital realm.

A Collaborative Ecosystem

San Diego's tech scene thrives on collaboration and community. The city's tech companies, large and small, foster an environment where ideas flow freely, sparking innovation. Startups find support in the city's network of entrepreneurs, investors, and mentors, enabling them to transform concepts into thriving businesses.

Future-Focused Tech Education

San Diego's reputation as a tech hub is bolstered by its commitment to education and research. The city is home to renowned universities like UC San Diego that offer people education and access to cutting edge computer science, engineering, and information technology products. These institutions are nurturing the next generation of tech talent, ensuring a continuous flow of fresh ideas and skilled professionals to technology companies and job opportunities for new grads.

Tech Companies for a New Era

San Diego tech stands as a testament to the power of tech innovation and collaboration. From software development to online media, the city's tech landscape is a mosaic of creativity and expertise. As San Diego's tech companies continue to craft the digital future, they are reshaping industries, enhancing experiences, and positioning the city as a technological force to be reckoned with.

List of companies headquartered in San Diego

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Splash logo
Splash is doing this again in the pool care market, and I understand what it takes to establish a successful, category-defining business in this space. We'd love to join you on this trip.
San DiegoCA1 - 102024$4,500,000
Mirador Therapeutics logo
Mirador Therapeutics envisions precision medicine for immune-mediated inflammatory and fibrotic diseases.
San DiegoCA10 - 502024$480,000,000
Piramidal logo
Piramidal offers artificial intelligence software that transforms brain activity into easy-to-understand health data to help diagnose neurological diseases.
San DiegoCA1 - 102024$6,500,000
Bench Talent Cloud logo
Bench Talent Cloud offers talent management services via a tech-enabled external talent community that serves as a virtual bench.
San DiegoCA1 - 102024$1,284,999
Candid Therapeutics logo
Developing innovative therapeutics to materially improve the lives of patients. We strive to be transparent and open in our goals, plans, and progress.
San DiegoCA2 - 102024$370,000,000
Primrose Bio logo
Primrose Bio is a biotech company that focuses on discovery, development, and manufacturing of new molecules. innovative therapeutics, vaccines and ingredients to aevance global health.
San DiegoCA50 - 2002023$14,999,999
Neurasync logo
Neurasync is a software company currently based in San Diego, California, United States. It has been founded in 2023.
San DiegoCA1 - 102023$3,300,000
Trainy logo
We're working on open source tooling to take the guesswork out of optimizing the speed of distributed model training. We've built a dashboard for understanding multi-gpu profiles and tools to train and serve LLMs that you can try right now. Check out our p
San DiegoCA2 - 102023$500,000
Steno.ai logo
Steno.ai provides custom AI that converts, activates, and engages users. Our solution integrates with existing websites, software, and apps to create a personalized AI experience that helps companies increase revenue.
San DiegoCA5 - 102023$120,000
Persperion Diagnostics logo
Persperion Diagnostics Inc. is a San Diego-based early-stage startup company working on developing a novel non-invasive sweat biomarker sensing technology.
San DiegoCA10 - 502022$3,999,998
Sonocharge Energy logo
Sonocharge Energy is developing a platform technology that enable a battery to have high power density and high energy density across the range of markets and applications.
San DiegoCA10 - 502022$15,099,997
Term Labs logo
Term Labs is a blockchain research and development business, is to provide scalable, transparent fixed-rate lending on blockchains. It helps to provide institutional-scale borrowers and lenders transparent, affordable, and crypto-native options.
San DiegoCA5 - 202022$8,500,000
Pathway Power logo
Pathway Power is a utility-scale solar and battery storage developer building renewables energy value chain.
San DiegoCA5 - 102022$61,000,000
Monarch Energy logo
Monarch Energy operates a green hydrogen project development platform. They convert abundant renewable power supplies into clean fuels to decarbonize segments of the economy that are difficult to electrify.
San DiegoCA5 - 102022$25,449,404
Firestorm Labs logo
Firestorm is building the future of modular open-source architecture supporting the Department of Defense requirements to create ''Low-Cost, Affordable Mass.''
San DiegoCA5 - 202022$40,519,500
Nocturne Labs logo
Nocturne is a system that allows for on-chain private accounts.
San DiegoCA2 - 102022$6,000,000
Ryne Biotechnology logo
Ryne Biotechnology focuses on developing therapies for neurodegenerative movement disorders. The company was founded in 2022 and is headquartered in Cambridge, Massachusetts, United States.
San DiegoCA5 - 102022$89,000,000
Cubist logo
Cubist brings modern software engineering practices and first-class security to web3 builders. Cubist’s toolkit makes it safe and easy to build, test and deploy multi-chain and cross-chain dapps in automated pipelines that handle keys and sequencing.
San DiegoCA5 - 202022$7,000,000
Yummers logo
Pet food is getting a big upgrade. Between ingredient lists as long as receipts and kibble that looks less than appetizing, the founders of Yummers knew we were long due for a change. That’s why they created meal mix-ins. From irresistible flavors to tempt
San DiegoCA10 - 502022$6,300,000
ISHI Health logo
ISHI Health is an AI-powered virtual clinic that offers personalized care to heart failure and cardiometabolic patients.
San DiegoCA2 - 102022$4,000,000
HUMBL Pay logo
HUMBL Pay simplifies and facilitates the use of digital assets such as BTC, ETH, and USDC.
San DiegoCA10 - 502021$2,500,000
VedaBio logo
VedaBio innovative platform for near-instant molecular detection of multiplexed analytes delivers best-in-class accuracy without the requirement for target amplification transforming molecular biology.
San DiegoCA20 - 502021$40,000,000
Splitero logo
Splitero is to provide homeowners with better options to access home equity without new debt or additional monthly payments.
San DiegoCA20 - 502021$317,500,000
Self Inspection logo
Self Inspection is redefining the vehicle inspection market, enabling companies to complete a computer vision-based guided vehicle inspection in a few minutes on any phone, using AI to evaluate damages and estimate fix costs. The tech streamlines lease-end
San DiegoCA5 - 202021$2,800,000
DockWorks logo
Were a seed-stage B2B SaaS startup, with over $1.8mm in funding from amazing SaaS investors. Our platform allows marine professionals to manage payments easily, simplify scheduling and dispatching, as well as provide technicians with the accurate and relia
San DiegoCA10 - 202021$1,750,000
Replicate Bioscience logo
Replicate Bioscience creates novel oncology treatments to prevent and reverse drug resistance through a self-replicating RNA platform called SynRGY. By deploying SynRGY technology, the company aims to design novel treatments that prevent the occurrence of
San DiegoCA20 - 502021$46,000,000
Excellos logo
Excellos is a developer and manufacturer of cell, gene therapies.
San DiegoCA20 - 502021$20,000,000
Adcentrx Therapeutics logo
Adcentrx is a biotechnology company focused on accelerating breakthroughs in protein conjugate therapeutic development for cancer and other life-threatening diseases. By combining the targeting precision of biologics and the disease fighting power of small
San DiegoCA20 - 502021$101,000,000
Capstan Therapeutics logo
Capstan Therapeutics is advancing precision in vivo cell engineering to develop therapeutics for a broad range of disease categories with unmet or underserved clinical need.
San DiegoCA100 - 5002021$340,000,000
Relay logo
Relay helps leaders run their teams more effectively by establishing the right workflows, running them on time, and automating tedious coordination.
San DiegoCA5 - 202021$8,100,000
Replay logo
Replay is a genome writing company, which aims to define the future of genomic medicine through reprogramming biology by writing and delivering big DNA.
San DiegoCA10 - 502021$55,000,000
LifeForce Games logo
We are a blockchain game studio, building a portfolio of jaw dropping experiences through interactive, persistent cloud based game worlds.
San DiegoCA5 - 202021$5,000,000
Looq AI logo
Looq AI is an enterprise software company that offers 3D survey and mapping services using artificial intelligence.
San DiegoCA10 - 502021$4,649,999
Sirius Therapeutics logo
Sirius Therapeutics is an innovative biotechnology company that focuses on RNAi therapies for cardiovascular diseases.
San DiegoCA2 - 102021$60,000,000
Kahoona logo
Kahoona, a first of its kind 1st Party Data activation platform for the open-web, provides an essential solution for a cookie-less and identity-less digital ecosystem. By utilizing our proprietary technology, with a focus on 1st Party Data alone, we are ab
San DiegoCA20 - 502021$4,500,000
Actio Biosciences logo
Actio Biosciences involves in the development of precision medicines for homogenous rare patient populations. They develop a pipeline of new medicines with the goal to enhance the probability of clinical success and deliver medicines for all patients.
San DiegoCA10 - 502021$55,000,000
Cloud Water Filters logo
Cloud is a water brand, building a network of lifelong customers around the single promise of toxin-free, nutrient-rich water. Their products are easy to use, technology-enabled, and deliver pure water peace of mind.
San DiegoCA5 - 102021$2,300,000
VertiCAL Farms logo
VertiCAL Farms is an aeroponics-based vertical farming startup (with a focus on technology) that looks to take advantage of modern approaches to nature. For inquiries, telephone and email contact are used.
San DiegoCA2 - 102021
Zafrens logo
Zafrens specializes in developing tools and generating insights at the interface of biology, chemistry, and engineering.The company was founded in 2021 and is headquartered in San Diego, California, United States.
San DiegoCA5 - 202021$29,000,000
CRISPR QC logo
Here at CRISPR QC, we empower scientists using CRISPR to solve the world’s great challenges by providing the key cornerstones of information and insight fundamental to realizing the full potential of CRISPR.
San DiegoCA10 - 502021$12,485,000
XinThera logo
XinThera is a drug discovery company focused on building small molecule oncology and immunology pipeline.
San DiegoCA20 - 502021$50,000,000
Alterome Therapeutics logo
Alterome Therapeutics is a precision oncology biotech developing alteration-specific therapeutics to address high value and validated oncogenic drivers.
San DiegoCA20 - 502021$231,000,000
Tachyon logo
Tachyon is a developer-first upload API, backed by a global network that makes big data transfer a breeze.
San DiegoCA2 - 102021
Palamedrix logo
Palamedrix is the first company to leverage DNA nanotechnology for revolutionary advancements in life science and medicine.
San DiegoCA2 - 102020$6,000,000
Hauler Hero logo
Delivering Technology for Waste & Recycling Hauler Operators
San DiegoCA20 - 502020$1,956,999
Momos logo
Running a restaurant in today’s world can be difficult. Momos helps restaurants maximize revenue and growth through its digital marketing, reputation management and analytics platform. Momos is dedicated to helping restaurants scale and build their busines
San DiegoCA50 - 2002020$16,500,000
Revelation Biosciences logo
Revelation Biosciences develops immunologic therapeutics and diagnostics designed to make the world a healthier place.
San DiegoCA5 - 202020$51,561,288
OnboardFlow logo
OnboardFlow is a software that helps in the conversion of trial customers through their SAAS platform that features analytics and insights.
San DiegoCA1 - 102020
Drata logo
Drata is an advanced security and compliance automation platform with the mission to help companies earn and keep the trust of their users, customers, partners, and prospects. Drata helps companies streamline their SOC 2 compliance through continuous, auto
San DiegoCA500 - 1,0002020$328,240,864
Lengo Therapeutics logo
Lengo Therapeutics a biopharmaceutical company focused on the discovery and development of cancer treatments. Lengo works to identify several mutations in cancers that were not well addressed by existing therapeutics, helping medical practitioners and phar
San DiegoCA10 - 502020$15,000,000
Lively Root logo
At Lively Root, we are horticultural experts passionate about empowering our customers to create green spaces. Our team has over a century of experience as growers, retailers, and landscapers. We know with so many new consumers to home gardening, the learn
San DiegoCA10 - 202020$5,100,000
Ocelot Bio logo
Ocelot Bio brings new treatment options to patients with severe liver disease. The company was founded in 2020 and is headquartered in San Diego, California.
San DiegoCA10 - 502020$39,000,000
Innovasion Labs PINC logo
Innovasion Labs PINC produces lithium-ion battery technology prototypes using technology that has undergone proof of concept testing in a laboratory setting.
San DiegoCA2 - 102020$2,000,000
Turquoise Health logo
Turquoise Health is a health care company that simplifies administration to reduce the expense and complexity of healthcare. The company was founded in 2020 and is headquartered in San Diego, California, United States.
San DiegoCA100 - 5002020$55,300,000
Longboard Pharmaceuticals Inc logo
Longboard Pharmaceuticals delivers medicines with optimized pharmacology and pharmacokinetics to patients with rare neurological diseases. Its proprietary pipeline includes multiple programs with broad clinical utility. Longboard is evaluating LP352, a nex
San DiegoCA50 - 1002020$1,596,968
EV Range logo
EV Charging Platform with in-house EPC, software development and support services for public and fleet electric transportation. Over 400 high power (180kW-1MW) ports deployed, with a fully integrated ecosystem for reliable, simple and supported experience.
San DiegoCA10 - 502020$4,000,000
FTN Network logo
FTN Network is a multi-site high-level data and media company focused on all things iGaming from traditional sports betting, season-long fantasy sports and daily fantasy sports. We cover all sports with proprietary data and tools that we incorporate in ou
San DiegoCA50 - 2002020$3,000,000
Pigeon Loans logo
Pigeon Loans is a peer-to-peer lending platform that facilitates loans between family, friends, and loved ones. The platform provides their users the ability to generate legal contracts, make online payments, store loan documentation, enable automatic bank
San DiegoCA5 - 202020$2,900,000
Alida Biosciences logo
Alida Biosciences is developing the next generation of RNA analysis tools to enable new medical treatments and diagnostic assays.
San DiegoCA10 - 502020$16,610,000
Trestle Biotherapeutics logo
Trestle Biotherapeutics is a biotechnology company that introduces bioengineered kidneys for patients with kidney disease. The company's services allow healthcare providers to reduce their reliance on dialysis while also enhancing the disease status of ren
San DiegoCA2 - 102020$1,000,000
TENTARIX BIOTHERAPEUTICS logo
Tentarix creates innovative protein therapeutics with uniquely combined bioactivities that leverage synthetic biology. The company develops a protein engineering platform designed for multispecific therapies.
San DiegoCA20 - 502020$93,000,000
Kate Therapeutics logo
Kate Therapeutics is a patient-focused biotechnology company developing AAV-based gene therapies to treat genetically defined muscle and heart diseases.
San DiegoCA20 - 502020$51,000,000
Genome Insight logo
Genome Insight is a whole genome sequence (WGS) analysis and interpretation company.
San DiegoCA1 - 2002020
Aegis Life logo
Our mission is to protect human health from the world’s most dangerous and persistent infectious diseases. We will do whatever it takes, leveraging our next-generation vaccines and therapeutics to end the current COVID-19 pandemic and counteract future out
San DiegoCA10 - 502020$4,450,000
BlossomHill Therapeutics logo
BlossomHill Therapeutics, Inc. is a small molecule drug discovery and development company focused on unmet medical needs in oncology and autoimmune disorders.
San DiegoCA20 - 502020$173,000,000
Look Sharp Labs logo
Adaptive Audio AI powering the future of music consumption in games and digital experiences
San DiegoCA20 - 502020$2,450,000
Soaak logo
Soaak Technologies provides transformation health solutions that use a “whole-person” approach to optimize your health and wellness. We believe that everyone should have 24/7 access to the help and support they need.
San DiegoCA10 - 502020$8,250,000
Neomorph logo
Neomorph is a venture backed biotechnology company based in San Diego, California. The team at Neomorph is building a leading protein degradation company, focusing on ‘molecular glue’ degraders. Our mission at Neomorph is to use this technology to solve cr
San DiegoCA50 - 1002020$109,000,000
RayzeBio logo
RayzeBio is focused on improving outcomes for people with cancer by harnessing the power of targeted radioisotopes. As the emerging leader in radiopharmaceuticals, RayzeBio is developing an innovative robust pipeline against validated oncology drug targets
San DiegoCA50 - 1002020$418,000,000
PiKNiK logo
PiKNiK & Company develops mining servers and enterprise storages to act as data storage partner for Web 3.0.
San DiegoCA20 - 502020$4,393,570
VECKTA logo
VECKTA is a cloud-based market platform that delivers full turnkey microgrid design and implementation solutions.
San DiegoCA20 - 502019$3,300,000
Vasa Therapeutics logo
Vasa Therapeutics is a privately held, preclinical-stage encinitas, CA-based biopharmaceutical company.
San DiegoCA10 - 502019$8,300,000
Ubiq Security logo
Ubiq is a technology company that has simplified the complex and messy world of encryption through a set of APIs, that are simple enough for any developer to use, yet scalable and extensible enough to encrypt data effortlessly across diverse applications a
San DiegoCA20 - 502019$6,400,000
Rowdy Energy logo
Rowdy Energy is a drink industry business that specializes in energy drinks. It combines caffeine with the nootropic L-Theanine to provide a powerful boost without the unwelcome and irritable crash. The company's L-Theanine gives the laser focus on the nee
San DiegoCA5 - 202019$13,000,000
ChargeNet Stations logo
ChargeNet Stations specializes in the fields of SaaS, cleantech, electric vehicle supply equipment, and distributed energy resources.
San DiegoCA20 - 502019$6,996,000
Sendamply logo
Amply is a cloud-based email delivery service. Amply’s analytics engine helps companies gain actionable insight around the email they send.
San DiegoCA2 - 102019$105,000
Engrail Therapeutics logo
Transforming the lives of patients with life-limiting diseases of the nervous system. Acquiring, developing and commercializing transformative medicines.
San DiegoCA20 - 502019$221,000,000
Alias logo
A better way to connect. Alias is the easiest way to connect and share your entire digital profile from one place. Download Alias from the App Store today! Created in 2019, Alias is the best way to connect with others and share your digital profile all f
San DiegoCA1 - 102019
Mosaic.tech logo
Mosaic.tech combines big data and machine learning that provides predictive reporting capabilities, leveling the playing field, and giving startups tools and insights for large enterprises. Its one-click integrations and real-time analytics offer clear ins
San DiegoCA100 - 2002019$71,900,000
Micronoma logo
Micronoma is developing early and specific cancer diagnostic assays using innovative microbial biomarkers from a simple blood sample
San DiegoCA20 - 502019$6,500,000
ADARx Pharmaceuticals logo
ADARx Pharmaceuticals is a genetic medicine company focusing on the base editing of mRNA transcripts.
San DiegoCA20 - 502019$332,000,000
HiDEF logo
Video Game Company HiDef Inc. Launches With $7.5M in Series A Funding
San DiegoCA10 - 502019$7,500,000
FutureProof Technologies logo
FutureProof Technologies is a financial analytics software company specializing in physical climate risks.
San DiegoCA20 - 502019$9,500,000
Inmagene Biopharmaceuticals logo
It is a leading biotech company focused on immunology-related therapeutic areas.
San DiegoCA50 - 1002019$121,000,000
Virtuity Financial Partners logo
Virtuity helps you build a stronger financial future through a deeper understanding of financial concepts, products, and services. Virtuity associates work with you to determine a financial strategy to serve your unique situation and help you pursue your g
San DiegoCA500 - 1,0002019
Entos logo
Entos uses machine learning-technology for energy and force evaluations required for R&D labs. Its technology assists in analyzing quantum molecular simulation. The software uses mean-field-cost quantum calculations to analyze the data for the atomic repre
San DiegoCA50 - 1002019$203,000,000
Function Oncology logo
Function Oncology is a precision medicine company advancing a CRISPR-powered personalized functional genomics platform to understand cancer in unprecedented and patient-specific detail. By moving beyond traditional gene sequencing to measuring gene functio
San DiegoCA5 - 202019$28,000,000
Debut logo
Debut creates natural ingredients using advanced biomanufacturing tools.
San DiegoCA100 - 5002019$66,200,000
858 Therapeutics logo
858 Therapeutics is a biotechnology and drug discovery company developing a portfolio of small molecule drugs that act on novel therapeutic targets in oncology, including proteins that regulate RNA and the innate immune response.
San DiegoCA20 - 502019$130,056,096
Algotive logo
We spearhead the artificial intelligence revolution by creating IoT devices, proprietary AI and ML core algorithms, and Smart Cloud Systems.
San DiegoCA20 - 502019$4,000,000
Pack Digital logo
We are an experienced team of individuals that work with lifestyle brands that have a story to tell. We love partnering with digital-focused brands to drive growth and we specialize in a select technology stack that provides the flexibility and agility nee
San DiegoCA20 - 502019$6,000,000
UNIGRID logo
UNIGRID develops sustainable and affordable sodium-based batteries using abundant materials. They aim to put a battery into every home, the grid, and other distributed energy storage applications. They use dense Na-alloy and a non-flammable electrolyte, wh
San DiegoCA5 - 102019$12,255,700
Ivy Energy logo
Ivy is a turn-key service powered by intelligent software providing equitable solar access to residents and predictable returns to owners.
San DiegoCA20 - 502019$18,000,000
MBrace Therapeutics logo
MBrace Therapeutics is a privately held biopharmaceutical business dedicated to improving cancer patients' quality of life by developing antibody-drug conjugates (ADCs) against novel oncology targets.
San DiegoCA10 - 502019$110,000,000
Una Travel Planner By XOKind logo
XOKind is an AI startup, formed with the mission of simplifying human planning and decision making by distilling the world's information, and we are launching our first product in the travel and leisure space.
San DiegoCA5 - 102019$3,600,000
Elevate Dynamics logo
Elevate Dynamics is a designer and manufacturer of healthcare products. The products are designed to improve mobility and eliminate pain through innovative design and manufacturing.
San DiegoCA10 - 502019$8,765,197
Faro Health logo
Faro Health is bringing clinical trials into the digital age by helping teams manage and balance the complexity of modern trial designs through a cloud native platform. The Faro platform enables study teams to design complex clinical trials using small mod
San DiegoCA20 - 502019$35,000,000
Serenity EHS logo
Environmental, Health, and Safety - Powered by ServiceNow
San DiegoCA10 - 502019$10,899,998
Payroll Integrations logo
Payroll Integrations offers their customers a plug-and-play data integration solution that enables 401(k) recordkeepers and TPAs to stay one step ahead of the competition. Its technological solution maintains plan administration and customer support while
San DiegoCA20 - 502019$20,750,000
Playable Worlds logo
Playable Worlds is a computer games company that specializes in the fields of game development, online games, and gamification. The company is driven by its mission is to build a truly cloud-native game, taking advantage of technology to create a true pers
San DiegoCA20 - 1002019$37,700,000
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